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normal human epidermal melanocytes (nhems)  (Kurabo industries)

 
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    Kurabo industries normal human epidermal melanocytes (nhems)
    Normal Human Epidermal Melanocytes (Nhems), supplied by Kurabo industries, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/normal+human+epidermal+melanocytes+nhem/normal+human+epidermal+melanocytes/pm40493564-67-0-8
    Average 90 stars, based on 1 article reviews
    normal human epidermal melanocytes (nhems) - by Bioz Stars, 2026-09
    90/100 stars

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    Article Title: Possible involvement of ERK 1/2 in UVA-induced melanogenesis in cultured normal human epidermal melanocytes.
    Article Snippet: Technical Research Laboratory, Kurabo Industries Ltd, Osaka 572-0823, Japan Central Research Institute, Sunstar Inc., Osaka 569-1195, Japan School of Pharmaceutical Sciences, Nagasaki Uni6ersity, Nagasaki 852-8521, Japan Radioisotope Institute, Nara Medical Uni6ersity, Nara 634-8521, Japan Radioisotope Center, Nagasaki Uni6ersity, Nagasaki 852-8523, Japan *Address reprint requests to Naoki Matsuda, Ph.D., Radioisotope Center, Nagasaki Uni6ersity, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.. E-mail: nuric@net.nagasaki-u.ac.jp

    Article Title: Inhibitory effects of 16-hydroxy-9-oxo-10E,12E,14E-octadecatrienoic acid (Corchorifatty acid B) isolated from Melissa officinalis Linné on melanogenesis.
    Article Snippet: 16-hydroxy-9-oxo-10E,12E,14E-octadecatrienoic acid, also known as Corchorifatty acid B (CFAB), is isolated from the ethanol extracts of the aerial parts of Melissa officinalis Linné (Labiatae) and exhibits inhibitory effects on cellular pigmentation in both human melanocytes and mouse melanoma B16 cells.. CFAB specifically decreases cellular melanin by most likely inducing rapid degradation of tyrosinase in B16 cells.. Interestingly, unlike other reagents that promote degradation of tyrosinase in proteasomes or lysosomes, neither proteasomal nor lysosomal inhibitors can halt CFAB-induced tyrosinase degradation.

    Article Title: Method for enhancing expression of antioxidant in epidermis
    Article Snippet: Normal human epidermal melanocytes (NHEM: from Kurabo Industries Ltd.) were seeded at a cell density of 2.0×104 cells/well in a 96-well culture plate using a medium (DermaLife (registered trademark) M Comp kit medium: from Kurabo Industries Ltd.).

    Article Title: Quantitative changes in the secretion of exosomes from keratinocytes homeostatically regulate skin pigmentation in a paracrine manner.
    Article Snippet: The content and distribution of melanin in the epidermis determines the wide variety of skin colors associated with ethnic/racial diversity.. Although it was previously reported that qualitative changes in keratinocyte-derived exosomes regulate melanocyte pigmentation in vitro, their practical involvement, especially in skin color development in vivo, has remained unclear.. To address this unexplained scientific concern, the correlation of epidermal exosomes isolated from human skin tissues with melanosomal protein expression levels was demonstrated in this study for the first time.

    Article Title: Method for enhancing expression of antioxidant in epidermis
    Article Snippet: Normal human epidermal melanocytes (NHEM: from Kurabo Industries Ltd.) were seeded at a cell density of 3.0×104 cells/well in a 96-well culture plate using a medium (DermaLife (registered trademark) M Comp kit medium: from Kurabo Industries Ltd.).



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    Identification of molecules that regulate the growth inhibitory effects of melanoma cells by delphinidin. ( a ) Schematic of genetic screening for molecules that mediate the inhibition of melanoma cell proliferation by delphinidin. ( b ) Fam222B protein levels in melanoma cell lines and <t>NHEMs</t> were assessed using Western blot analysis ( n = 1). ( c and d ) Fam222B mRNA expression and protein levels were evaluated in B16 cells treated with delphinidin for 48 h ( n = 3). Data are presented as mean ± SEM. Statistical analysis was conducted using one-way ANOVA followed by Dunnett’s multiple comparison test.
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    Identification of molecules that regulate the growth inhibitory effects of melanoma cells by delphinidin. ( a ) Schematic of genetic screening for molecules that mediate the inhibition of melanoma cell proliferation by delphinidin. ( b ) Fam222B protein levels in melanoma cell lines and NHEMs were assessed using Western blot analysis ( n = 1). ( c and d ) Fam222B mRNA expression and protein levels were evaluated in B16 cells treated with delphinidin for 48 h ( n = 3). Data are presented as mean ± SEM. Statistical analysis was conducted using one-way ANOVA followed by Dunnett’s multiple comparison test.

    Journal: Scientific Reports

    Article Title: Delphinidin upregulates microRNA-let-7b expression through family with sequence similarity 222 member B

    doi: 10.1038/s41598-025-15588-3

    Figure Lengend Snippet: Identification of molecules that regulate the growth inhibitory effects of melanoma cells by delphinidin. ( a ) Schematic of genetic screening for molecules that mediate the inhibition of melanoma cell proliferation by delphinidin. ( b ) Fam222B protein levels in melanoma cell lines and NHEMs were assessed using Western blot analysis ( n = 1). ( c and d ) Fam222B mRNA expression and protein levels were evaluated in B16 cells treated with delphinidin for 48 h ( n = 3). Data are presented as mean ± SEM. Statistical analysis was conducted using one-way ANOVA followed by Dunnett’s multiple comparison test.

    Article Snippet: Mouse melanoma B16 cells, human melanoma cell lines (A375, Hs294t, and MeWo), and normal human epidermal melanocytes (NHEMs) were obtained from the American Type Culture Collection (Manassas, VA, USA).

    Techniques: Inhibition, Western Blot, Expressing, Comparison